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CHEM-4300 - Medicinal Chemistry
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< meta property = "og:description" content = "This course explores the fundamental principles that define the relationship between chemical structure and the biological action of drug molecules. A major focus of the course is the application of these chemical principles to molecular-targeted drug discovery, molecular mechanisms of pharmacological activity, and the biopharmaceutical properties of drugs. The relationships between drug structure, therapeutic properties, and physicochemical characteristics will be discussed. Structure activity relationships (SAR), structure-property relationships (SPR) and ADME (absorption, distribution, metabolism, and excretion) will be explored and presented through case studies. The roles of computational chemistry, molecular modeling, and biophysical methods in the understanding of the relationship between structure and biological activity will also be studied. Although an emphasis will be placed on orally bioavailable small molecules, alternative drug modalities will also be discussed." >
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Medicinal Chemistry
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CHEM-4300
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This course explores the fundamental principles that define the relationship between chemical structure and the biological action of drug molecules. A major focus of the course is the application of these chemical principles to molecular-targeted drug discovery, molecular mechanisms of pharmacological activity, and the biopharmaceutical properties of drugs. The relationships between drug structure, therapeutic properties, and physicochemical characteristics will be discussed. Structure activity relationships (SAR), structure-property relationships (SPR) and ADME (absorption, distribution, metabolism, and excretion) will be explored and presented through case studies. The roles of computational chemistry, molecular modeling, and biophysical methods in the understanding of the relationship between structure and biological activity will also be studied. Although an emphasis will be placed on orally bioavailable small molecules, alternative drug modalities will also be discussed.
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4 credits
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Cross-listed with:
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< a class = "course-pill" href = "CHEM-6300.html" > CHEM-6300 Medicinal Chemistry< / a >
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Prereqs:
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< a class = "course-pill" href = "CHEM-2260.html" > CHEM-2260 Organic Chemistry II< / a >
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Past Term Data
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Offered
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Not Offered
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Offered as Cross-Listing Only
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No Term Data
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Simple View
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Detailed View
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< th class = "spring season-label" > Spring< / th >
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< th class = "summer2 midsum-label" > (Session 1)< / th >
< th class = "summer3 midsum-label" > (Session 2)< / th >
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< th class = "year" > 2023< / th >
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< th class = "year" > 2022< / th >
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< th class = "year" > 2021< / th >
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< th class = "year" > 2020< / th >
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< th class = "year" > 2017< / th >
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Medicinal Chemistry (4c)
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< ul class = "prof-list" >
< li > Robert Jason Herr< / li >
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Seats Taken: 0/25
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Medicinal Chemistry (4c)
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< ul class = "prof-list" >
< li > Mark Wentland< / li >
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Seats Taken: 19/25
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< th class = "year" > 2013< / th >
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Medicinal Chemistry (4c)
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< li > Mark Wentland< / li >
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Seats Taken: 18/30
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< th class = "year" > 2012< / th >
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Medicinal Chemistry (4c)
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< li > Mark Wentland< / li >
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Seats Taken: 22/30
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< th class = "year" > 2011< / th >
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Medicinal Chemistry (4c)
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< li > Mark Wentland< / li >
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Seats Taken: 19/30
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Medicinal Chemistry (4c)
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< ul class = "prof-list" >
< li > Mark Wentland< / li >
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Seats Taken: 32/25
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< th class = "year" > 2009< / th >
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Medicinal Chemistry (4c)
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< ul class = "prof-list" >
< li > Mark Wentland< / li >
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< span class = "course-capacity" >
Seats Taken: 10/25
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