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CHEM-4330: Drug Discovery
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<meta property="og:description" content="This course will examine how bioinformatics, functional genomics, and other modern biotechnologies are used to speed the discovery of new drugs, especially those small organic molecules to treat human diseases with large unmet therapeutic need. Special emphasis will be placed on molecular target identification and validation as well as high-throughput screening to identify a lead. Topics to be discussed will include transgenic mice, RNA interference, DNA and protein microarrays, homogenous time-resolved fluorescence bioassays, phage-display, combinatorial chemistry, and parallel synthesis.">
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<h1 id="name">
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Drug Discovery
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<h2 id="code">
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CHEM-4330
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</h2>
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<p>
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This course will examine how bioinformatics, functional genomics, and other modern biotechnologies are used to speed the discovery of new drugs, especially those small organic molecules to treat human diseases with large unmet therapeutic need. Special emphasis will be placed on molecular target identification and validation as well as high-throughput screening to identify a lead. Topics to be discussed will include transgenic mice, RNA interference, DNA and protein microarrays, homogenous time-resolved fluorescence bioassays, phage-display, combinatorial chemistry, and parallel synthesis.
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3 credits
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Cross-listed with:
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<div id=crosslist-classes" class="rel-info-courses">
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<a class="course-pill" href="CHEM-6330">CHEM-6330 Drug Discovery</a>
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Prereqs:
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one of:
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<a class="course-pill" href="CHEM-2220">CHEM-2220 Organic Synthesis</a>
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<a class="course-pill" href="CHEM-2260">CHEM-2260 Organic Chemistry II</a>
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Detailed View
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<table id="years-table">
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<thead>
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<th class="spring season-label">Spring</th>
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<th class="summer season-label" colspan="2">Summer</th>
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<th class="fall season-label">Fall</th>
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<tr>
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<th colspan="2"></th>
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<th class="summer2 midsum-label">(Session 1)</th>
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<th class="summer3 midsum-label">(Session 2)</th>
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<th></th>
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</tr>
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</thead>
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<tbody>
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<tr>
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<th class="year">2024</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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<th class="year">2023</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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<th class="year">2022</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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<tr>
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<th class="year">2021</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2020</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2019</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2018</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2017</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2016</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2015</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2014</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2013</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=201309&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c)</a>
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</span>
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<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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Seats Taken: 34/43
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2012</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=201209&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c)</a>
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</span>
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<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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Seats Taken: 26/43
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2011</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=201109&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c)</a>
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</span>
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<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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Seats Taken: 30/43
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2010</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=201009&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c)</a>
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</span>
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<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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Seats Taken: 24/43
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2009</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200909&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c)</a>
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</span>
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<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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Seats Taken: 25/43
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2008</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200809&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c)</a>
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</span>
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<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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Seats Taken: 24/48
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2007</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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|
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200709&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c)</a>
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</span>
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<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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|
Seats Taken: 31/48
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2006</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
|
|
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200609&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c) [WI]</a>
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</span>
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<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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|
Seats Taken: 34/40
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2005</th>
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<td class="term spring not-offered">
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2004</th>
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<td class="term spring offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200401&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (4c) [WI]</a>
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</span>
|
|
<ul class="prof-list">
|
|
<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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Seats Taken: 15/32
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</span>
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</div>
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200409&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (3c) [WI]</a>
|
|
</span>
|
|
<ul class="prof-list">
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<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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Seats Taken: 11/20
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</span>
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</div>
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</td>
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</tr>
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<tr>
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<th class="year">2003</th>
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<td class="term spring offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200301&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (4c) [WI]</a>
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|
</span>
|
|
<ul class="prof-list">
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|
<li>Mark Wentland</li>
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</ul>
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<span class="course-capacity">
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|
Seats Taken: 18/32
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</span>
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</div>
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</td>
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<td colspan="2" class="term summer not-offered">
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</td>
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<td class="term fall not-offered">
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</td>
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</tr>
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<tr>
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<th class="year">2002</th>
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<td class="term spring offered">
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<div class="view-container detail-view-container">
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<span class="term-course-info">
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|
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200201&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (4c) [WI]</a>
|
|
</span>
|
|
<ul class="prof-list">
|
|
<li>Mark Wentland</li>
|
|
</ul>
|
|
<span class="course-capacity">
|
|
Seats Taken: 14/16
|
|
</span>
|
|
</div>
|
|
</td>
|
|
<td colspan="2" class="term summer not-offered">
|
|
</td>
|
|
<td class="term fall not-offered">
|
|
</td>
|
|
</tr>
|
|
<tr>
|
|
<th class="year">2001</th>
|
|
<td class="term spring offered">
|
|
<div class="view-container detail-view-container">
|
|
<span class="term-course-info">
|
|
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200101&subj_in=CHEM&crse_in=4330&schd_in=">Drug Discovery (4c) [WI]</a>
|
|
</span>
|
|
<ul class="prof-list">
|
|
<li>Mark Wentland</li>
|
|
</ul>
|
|
<span class="course-capacity">
|
|
Seats Taken: 14/32
|
|
</span>
|
|
</div>
|
|
</td>
|
|
<td colspan="2" class="term summer not-offered">
|
|
</td>
|
|
<td class="term fall not-offered">
|
|
</td>
|
|
</tr>
|
|
<tr>
|
|
<th class="year">2000</th>
|
|
<td class="term spring not-offered">
|
|
</td>
|
|
<td colspan="2" class="term summer not-offered">
|
|
</td>
|
|
<td class="term fall not-offered">
|
|
</td>
|
|
</tr>
|
|
<tr>
|
|
<th class="year">1999</th>
|
|
<td class="term spring not-offered">
|
|
</td>
|
|
<td colspan="2" class="term summer not-offered">
|
|
</td>
|
|
<td class="term fall not-offered">
|
|
</td>
|
|
</tr>
|
|
<tr>
|
|
<th class="year">1998</th>
|
|
<td class="term spring unscheduled">
|
|
</td>
|
|
<td colspan="2" class="term summer not-offered">
|
|
</td>
|
|
<td class="term fall not-offered">
|
|
</td>
|
|
</tr>
|
|
</tbody>
|
|
</table>
|
|
</div>
|
|
</div>
|
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</body>
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</html>
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