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<title>
CHME-6470: Downstream Processing in Biochemical Engineering
</title>
<meta property="og:title" content="CHME-6470: Downstream Processing in Biochemical Engineering">
<meta property="og:description" content="The course focuses on the concentration, recovery, and isolation of biological molecules relevant in biotechnology. The characteristics of biological molecules such as proteins and biological fluids such as blood, fermentation, and cell culture broth, are discussed. The principles, advantages, and limitations of centrifugation, membranes, cell-disruption, two-phase extraction, precipitation crystallization, and electrical processes are discussed. Integrated bioseparation schemes are presented and many specific applications are discussed in detail.">
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<h1 id="name">
Downstream Processing in Biochemical Engineering
</h1>
<h2 id="code">
CHME-6470
</h2>
<p>
The course focuses on the concentration, recovery, and isolation of biological molecules relevant in biotechnology. The characteristics of biological molecules such as proteins and biological fluids such as blood, fermentation, and cell culture broth, are discussed. The principles, advantages, and limitations of centrifugation, membranes, cell-disruption, two-phase extraction, precipitation crystallization, and electrical processes are discussed. Integrated bioseparation schemes are presented and many specific applications are discussed in detail.
</p>
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3 credits
</span>
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Prereqs:
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none
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Past Term Data
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<table id="years-table">
<thead>
<tr>
<th></th>
<th class="spring season-label">Spring</th>
<th class="summer season-label" colspan="2">Summer</th>
<th class="fall season-label">Fall</th>
</tr>
<tr>
<th colspan="2"></th>
<th class="summer2 midsum-label">(Session 1)</th>
<th class="summer3 midsum-label">(Session 2)</th>
<th></th>
</tr>
</thead>
<tbody>
<tr>
<th class="year">2023</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2022</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2021</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2020</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2019</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2018</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2017</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2016</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2015</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2014</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2013</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall offered">
<div class="view-container detail-view-container">
<span class="term-course-info">
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=201309&subj_in=CHME&crse_in=6470&schd_in=">Downstream Bioprocessing (3c)</a>
</span>
<ul class="prof-list">
<li>Georges Belfort</li>
</ul>
<span class="course-capacity">
Seats Taken: 9/20
</span>
</div>
</td>
</tr>
<tr>
<th class="year">2012</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2011</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2010</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2009</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall offered">
<div class="view-container detail-view-container">
<span class="term-course-info">
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200909&subj_in=CHME&crse_in=6470&schd_in=">Downstream Bioprocessing (3c)</a>
</span>
<ul class="prof-list">
<li>Georges Belfort</li>
</ul>
<span class="course-capacity">
Seats Taken: 10/25
</span>
</div>
</td>
</tr>
<tr>
<th class="year">2008</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2007</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2006</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall offered">
<div class="view-container detail-view-container">
<span class="term-course-info">
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200609&subj_in=CHME&crse_in=6470&schd_in=">Downstream Bioprocessing (3c)</a>
</span>
<ul class="prof-list">
<li>Georges Belfort</li>
</ul>
<span class="course-capacity">
Seats Taken: 9/15
</span>
</div>
</td>
</tr>
<tr>
<th class="year">2005</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2004</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2003</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall offered">
<div class="view-container detail-view-container">
<span class="term-course-info">
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200309&subj_in=CHME&crse_in=6470&schd_in=">Downstream Bioprocessing (3c)</a>
</span>
<ul class="prof-list">
<li>Georges Belfort</li>
</ul>
<span class="course-capacity">
Seats Taken: 12/15
</span>
</div>
</td>
</tr>
<tr>
<th class="year">2002</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2001</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">2000</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall offered">
<div class="view-container detail-view-container">
<span class="term-course-info">
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=200009&subj_in=CHME&crse_in=6470&schd_in=">Downstream Bioprocessing (3c)</a>
</span>
<ul class="prof-list">
<li>Georges Belfort</li>
</ul>
<span class="course-capacity">
Seats Taken: 12/20
</span>
</div>
</td>
</tr>
<tr>
<th class="year">1999</th>
<td class="term spring not-offered">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall not-offered">
</td>
</tr>
<tr>
<th class="year">1998</th>
<td class="term spring unscheduled">
</td>
<td colspan="2" class="term summer not-offered">
</td>
<td class="term fall offered">
<div class="view-container detail-view-container">
<span class="term-course-info">
<a href="https://sis.rpi.edu/rss/bwckctlg.p_disp_listcrse?term_in=199809&subj_in=CHME&crse_in=6470&schd_in=">Downstream Bioprocessing (3c)</a>
</span>
<ul class="prof-list">
<li>Georges Belfort</li>
</ul>
<span class="course-capacity">
Seats Taken: 9/20
</span>
</div>
</td>
</tr>
</tbody>
</table>
</div>
</div>
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