Medicinal Chemistry

CHEM-6300

This course explores the fundamental principles that define the relationship between chemical structure and the biological action of drug molecules. A major focus of the course is the application of these chemical principles to molecular-targeted drug discovery, molecular mechanisms of pharmacological activity, and the biopharmaceutical properties of drugs. The relationships between drug structure, therapeutic properties, and physicochemical characteristics will be discussed. Structure activity relationships (SAR), structure-property relationships (SPR) and ADME (absorption, distribution, metabolism, and excretion) will be explored and presented through case studies. The roles of computational chemistry, molecular modeling, and biophysical methods in the understanding of the relationship between structure and biological activity will also be studied. Although an emphasis will be placed on orally bioavailable small molecules, alternative drug modalities will also be discussed.Â

3 credits
Cross-listed with:

Past Term Data

Offered
Not Offered
Offered as Cross-Listing Only
No Term Data
Spring Summer Fall
(Session 1) (Session 2)
2023
2022
2021
2020
2019
2018
2017
Medicinal Chemistry (3c)
  • Robert Jason Herr
Seats Taken: 0/25
2016
2015
2014
Medicinal Chemistry (3c)
  • Mark Wentland
Seats Taken: 3/25
2013
Medicinal Chemistry (3c)
  • Mark Wentland
Seats Taken: 2/30
2012
Medicinal Chemistry (3c)
  • Mark Wentland
Seats Taken: 6/30
2011
Medicinal Chemistry (3c)
  • Mark Wentland
Seats Taken: 5/30
2010
Medicinal Chemistry (3c)
  • Mark Wentland
Seats Taken: 1/0
2009
Medicinal Chemistry (3c)
  • Mark Wentland
Seats Taken: 6/10
2008
2007