The course presents several aspects of drug and gene delivery including: 1) definitions of what drugs or genes are; 2) pharmacokinetics and pharmacodynamics; 3) biomaterial selection considerations; 4) bioactivity considerations; 5) physiological and biochemical barriers to drug delivery; 6) diffusion controlled, dissolution controlled, and osmotic controlled drug delivery systems; 7) polymeric delivery systems; 8) ligand-based targeting and physical targeting; 9) viral mediated gene delivery; 10) non-viral gene delivery; 11) polymers in gene delivery.
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1998 |