# Medicinal Chemistry

## CHEM-4300

This course explores the fundamental principles that define the relationship between chemical structure and the biological action of drug molecules. A major focus of the course is the application of these chemical principles to molecular-targeted drug discovery, molecular mechanisms of pharmacological activity, and the biopharmaceutical properties of drugs. The relationships between drug structure, therapeutic properties, and physicochemical characteristics will be discussed. Structure activity relationships (SAR), structure-property relationships (SPR) and ADME (absorption, distribution, metabolism, and excretion) will be explored and presented through case studies. The roles of computational chemistry, molecular modeling, and biophysical methods in the understanding of the relationship between structure and biological activity will also be studied. Although an emphasis will be placed on orally bioavailable small molecules, alternative drug modalities will also be discussed.

3 credits
Cross-listed with:
CHEM-6300 Medicinal Chemistry
Prereqs:
CHEM-2260 Organic Chemistry II

# Past Term Data
Offered
Not Offered
Offered as Cross-Listing Only
No Term Data
Simple View
Detailed View

| Spring | Summer | Fall
--- | --- | --- | ---
| (Session 1) | (Session 2) |
2026 |  |  |

2025

Medicinal Chemistry (3c)

- Christopher Lawrence Cioffi

Seats Taken: 14/14

2024

Medicinal Chemistry (3c)

- Christopher Lawrence Cioffi

Seats Taken: 4/20

Medicinal Chemistry (3c)

- Christopher Lawrence Cioffi

Seats Taken: 9/14

2023 |  |  |
2022 |  |  |
2021 |  |  |
2020 |  |  |
2019 |  |  |
2018 |  |  |

2017

Medicinal Chemistry (4c)

- Robert Jason Herr

Seats Taken: 0/25

2016 |  |  |
2015 |  |  |

2014

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 19/25

2013

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 18/30

2012

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 22/30

2011

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 19/30

2010

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 32/25

2009

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 10/25

2008 |  |  |

2007

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 21/21

2006 |  |  |

2005

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 10/20

2004 |  |  |
2003 |  |  |
2002 |  |  |
2001 |  |  |

2000

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 18/40

1999 |  |  |

1998

Medicinal Chemistry (4c)

- Mark Wentland

Seats Taken: 26/60