diff --git a/src/video_core/renderer_opengl/gl_rasterizer_cache.cpp b/src/video_core/renderer_opengl/gl_rasterizer_cache.cpp
index f9b4a4b877..3a00d93831 100644
--- a/src/video_core/renderer_opengl/gl_rasterizer_cache.cpp
+++ b/src/video_core/renderer_opengl/gl_rasterizer_cache.cpp
@@ -88,6 +88,8 @@ static constexpr std::array<FormatTuple, SurfaceParams::MaxPixelFormat> tex_form
     // DepthStencil formats
     {GL_DEPTH24_STENCIL8, GL_DEPTH_STENCIL, GL_UNSIGNED_INT_24_8, ComponentType::UNorm,
      false}, // Z24S8
+    {GL_DEPTH24_STENCIL8, GL_DEPTH_STENCIL, GL_UNSIGNED_INT_24_8, ComponentType::UNorm,
+     false}, // S8Z24
 }};
 
 static const FormatTuple& GetFormatTuple(PixelFormat pixel_format, ComponentType component_type) {
@@ -131,13 +133,6 @@ MathUtil::Rectangle<u32> SurfaceParams::GetRect() const {
     return {0, actual_height, width, 0};
 }
 
-static void ConvertASTCToRGBA8(std::vector<u8>& data, PixelFormat format, u32 width, u32 height) {
-    u32 block_width{};
-    u32 block_height{};
-    std::tie(block_width, block_height) = GetASTCBlockSize(format);
-    data = Tegra::Texture::ASTC::Decompress(data, width, height, block_width, block_height);
-}
-
 template <bool morton_to_gl, PixelFormat format>
 void MortonCopy(u32 stride, u32 block_height, u32 height, u8* gl_buffer, Tegra::GPUVAddr addr) {
     constexpr u32 bytes_per_pixel = SurfaceParams::GetFormatBpp(format) / CHAR_BIT;
@@ -177,6 +172,7 @@ static constexpr std::array<void (*)(u32, u32, u32, u8*, Tegra::GPUVAddr),
         MortonCopy<true, PixelFormat::DXT1>,         MortonCopy<true, PixelFormat::DXT23>,
         MortonCopy<true, PixelFormat::DXT45>,        MortonCopy<true, PixelFormat::DXN1>,
         MortonCopy<true, PixelFormat::ASTC_2D_4X4>,  MortonCopy<true, PixelFormat::Z24S8>,
+        MortonCopy<true, PixelFormat::S8Z24>,
 };
 
 static constexpr std::array<void (*)(u32, u32, u32, u8*, Tegra::GPUVAddr),
@@ -197,6 +193,7 @@ static constexpr std::array<void (*)(u32, u32, u32, u8*, Tegra::GPUVAddr),
         nullptr,
         MortonCopy<false, PixelFormat::ABGR8>,
         MortonCopy<false, PixelFormat::Z24S8>,
+        MortonCopy<false, PixelFormat::S8Z24>,
 };
 
 // Allocate an uninitialized texture of appropriate size and format for the surface
@@ -234,6 +231,71 @@ CachedSurface::CachedSurface(const SurfaceParams& params) : params(params) {
                            rect.GetWidth(), rect.GetHeight());
 }
 
+static void ConvertS8Z24ToZ24S8(std::vector<u8>& data, u32 width, u32 height) {
+    union S8Z24 {
+        BitField<0, 24, u32> z24;
+        BitField<24, 8, u32> s8;
+    };
+    static_assert(sizeof(S8Z24) == 4, "S8Z24 is incorrect size");
+
+    union Z24S8 {
+        BitField<0, 8, u32> s8;
+        BitField<8, 24, u32> z24;
+    };
+    static_assert(sizeof(Z24S8) == 4, "Z24S8 is incorrect size");
+
+    S8Z24 input_pixel{};
+    Z24S8 output_pixel{};
+    for (size_t y = 0; y < height; ++y) {
+        for (size_t x = 0; x < width; ++x) {
+            const size_t offset{y * width + x};
+            std::memcpy(&input_pixel, &data[offset], sizeof(S8Z24));
+            output_pixel.s8.Assign(input_pixel.s8);
+            output_pixel.z24.Assign(input_pixel.z24);
+            std::memcpy(&data[offset], &output_pixel, sizeof(Z24S8));
+        }
+    }
+}
+/**
+ * Helper function to perform software conversion (as needed) when loading a buffer from Switch
+ * memory. This is for Maxwell pixel formats that cannot be represented as-is in OpenGL or with
+ * typical desktop GPUs.
+ */
+static void ConvertFormatAsNeeded_LoadGLBuffer(std::vector<u8>& data, PixelFormat pixel_format,
+                                               u32 width, u32 height) {
+    switch (pixel_format) {
+    case PixelFormat::ASTC_2D_4X4: {
+        // Convert ASTC pixel formats to RGBA8, as most desktop GPUs do not support ASTC.
+        u32 block_width{};
+        u32 block_height{};
+        std::tie(block_width, block_height) = GetASTCBlockSize(pixel_format);
+        data = Tegra::Texture::ASTC::Decompress(data, width, height, block_width, block_height);
+        break;
+    }
+    case PixelFormat::S8Z24:
+        // Convert the S8Z24 depth format to Z24S8, as OpenGL does not support S8Z24.
+        ConvertS8Z24ToZ24S8(data, width, height);
+        break;
+    }
+}
+
+/**
+ * Helper function to perform software conversion (as needed) when flushing a buffer to Switch
+ * memory. This is for Maxwell pixel formats that cannot be represented as-is in OpenGL or with
+ * typical desktop GPUs.
+ */
+static void ConvertFormatAsNeeded_FlushGLBuffer(std::vector<u8>& /*data*/, PixelFormat pixel_format,
+                                                u32 /*width*/, u32 /*height*/) {
+    switch (pixel_format) {
+    case PixelFormat::ASTC_2D_4X4:
+    case PixelFormat::S8Z24:
+        LOG_CRITICAL(Render_OpenGL, "Unimplemented pixel_format={}",
+                     static_cast<u32>(pixel_format));
+        UNREACHABLE();
+        break;
+    }
+}
+
 MICROPROFILE_DEFINE(OpenGL_SurfaceLoad, "OpenGL", "Surface Load", MP_RGB(128, 64, 192));
 void CachedSurface::LoadGLBuffer() {
     ASSERT(params.type != SurfaceType::Fill);
@@ -256,10 +318,7 @@ void CachedSurface::LoadGLBuffer() {
             params.width, params.block_height, params.height, gl_buffer.data(), params.addr);
     }
 
-    if (IsPixelFormatASTC(params.pixel_format)) {
-        // ASTC formats are converted to RGBA8 in software, as most PC GPUs do not support this
-        ConvertASTCToRGBA8(gl_buffer, params.pixel_format, params.width, params.height);
-    }
+    ConvertFormatAsNeeded_LoadGLBuffer(gl_buffer, params.pixel_format, params.width, params.height);
 }
 
 MICROPROFILE_DEFINE(OpenGL_SurfaceFlush, "OpenGL", "Surface Flush", MP_RGB(128, 192, 64));
@@ -272,6 +331,9 @@ void CachedSurface::FlushGLBuffer() {
 
     MICROPROFILE_SCOPE(OpenGL_SurfaceFlush);
 
+    ConvertFormatAsNeeded_FlushGLBuffer(gl_buffer, params.pixel_format, params.width,
+                                        params.height);
+
     if (!params.is_tiled) {
         std::memcpy(dst_buffer, gl_buffer.data(), params.size_in_bytes);
     } else {
diff --git a/src/video_core/renderer_opengl/gl_rasterizer_cache.h b/src/video_core/renderer_opengl/gl_rasterizer_cache.h
index 459abbdc2b..7aaf371bda 100644
--- a/src/video_core/renderer_opengl/gl_rasterizer_cache.h
+++ b/src/video_core/renderer_opengl/gl_rasterizer_cache.h
@@ -41,6 +41,7 @@ struct SurfaceParams {
 
         // DepthStencil formats
         Z24S8 = 13,
+        S8Z24 = 14,
 
         MaxDepthStencilFormat,
 
@@ -92,6 +93,7 @@ struct SurfaceParams {
             4, // DXN1
             4, // ASTC_2D_4X4
             1, // Z24S8
+            1, // S8Z24
         }};
 
         ASSERT(static_cast<size_t>(format) < compression_factor_table.size());
@@ -117,6 +119,7 @@ struct SurfaceParams {
             64,  // DXN1
             32,  // ASTC_2D_4X4
             32,  // Z24S8
+            32,  // S8Z24
         }};
 
         ASSERT(static_cast<size_t>(format) < bpp_table.size());
@@ -128,6 +131,8 @@ struct SurfaceParams {
 
     static PixelFormat PixelFormatFromDepthFormat(Tegra::DepthFormat format) {
         switch (format) {
+        case Tegra::DepthFormat::S8_Z24_UNORM:
+            return PixelFormat::S8Z24;
         case Tegra::DepthFormat::Z24_S8_UNORM:
             return PixelFormat::Z24S8;
         default:
@@ -226,6 +231,8 @@ struct SurfaceParams {
 
     static Tegra::DepthFormat DepthFormatFromPixelFormat(PixelFormat format) {
         switch (format) {
+        case PixelFormat::S8Z24:
+            return Tegra::DepthFormat::S8_Z24_UNORM;
         case PixelFormat::Z24S8:
             return Tegra::DepthFormat::Z24_S8_UNORM;
         default:
@@ -274,6 +281,7 @@ struct SurfaceParams {
 
     static ComponentType ComponentTypeFromDepthFormat(Tegra::DepthFormat format) {
         switch (format) {
+        case Tegra::DepthFormat::S8_Z24_UNORM:
         case Tegra::DepthFormat::Z24_S8_UNORM:
             return ComponentType::UNorm;
         default:
diff --git a/src/video_core/textures/decoders.cpp b/src/video_core/textures/decoders.cpp
index 680f22ddb8..7b06fea3e2 100644
--- a/src/video_core/textures/decoders.cpp
+++ b/src/video_core/textures/decoders.cpp
@@ -76,6 +76,7 @@ u32 BytesPerPixel(TextureFormat format) {
 
 static u32 DepthBytesPerPixel(DepthFormat format) {
     switch (format) {
+    case DepthFormat::S8_Z24_UNORM:
     case DepthFormat::Z24_S8_UNORM:
         return 4;
     default:
@@ -129,6 +130,7 @@ std::vector<u8> UnswizzleDepthTexture(VAddr address, DepthFormat format, u32 wid
     std::vector<u8> unswizzled_data(width * height * bytes_per_pixel);
 
     switch (format) {
+    case DepthFormat::S8_Z24_UNORM:
     case DepthFormat::Z24_S8_UNORM:
         CopySwizzledData(width, height, bytes_per_pixel, bytes_per_pixel, data,
                          unswizzled_data.data(), true, block_height);